Global Health Sciences

Zimbabwe health workers receive PPE from donors

Global Health Sciences

Overview

Our Global Health Sciences team aims to lower costs, improve quality, and increase access to treatment for millions of people in resource-limited settings by helping to develop less expensive and more effective versions of critical medications for adults and children; developing techniques and technologies that advance our understanding and management of diseases; and improving patient care. Five teams within Global Health Sciences provide technical insight and solutions across CHAI-supported countries and programs as well as to commercial entities, regulatory and normative organizations, and academic partners.

Analytics and Implementation Research

The Analytics and Implementation Research team supports CHAI’s mission to transform global health through: evaluations that test effectiveness and cost of innovations in real-world health settings and measure success; models that calculate the expected impact and cost of health programs and strengthen government capacity to prioritize investments; implementation research that accelerates the implementation and scale-up of highly effective interventions; data solutions that strengthen health systems; and translation and dissemination of knowledge and credible results that inform national and global level policy. The team includes public health scientists with broad experience in biostatistics, epidemiology, economics, and disease expertise.

Clinical Sciences

Health care products are important to restore and maintain health, yet these products must be administered correctly to optimize benefits and minimize risks. The Clinical Sciences team develops strategies and technologies that advance our understanding of disease and improve the delivery of health services. We interpret and share trends and research in global health to ensure CHAI’s work is well-informed and impactful; train and mentor colleagues on treatment guidelines and standards of care in resource-limited settings; and develop global and national public health policies. CHAI senior clinicians also use their personal experience managing patients to inform our work. This can be a valuable resource when emerging conditions lack evidence or normative guidance, as was the case for COVID-19.

Product Development, Quality, Costing, and Regulatory Affairs

CHAI accelerates affordable access to quality-assured medical products for people living in low- and middle-income countries. Working with innovator and generic suppliers and other global stakeholders across disease areas, we support product development and market introduction, while maintaining a relentless commitment to quality, safety, effectiveness, and affordability, and stringent regulatory standards.

Results

US$1.2B
in expected savings over 7 years in generic-accessible ARV markets in low-and middle-income countries through transition to DTG
12
countries provided with national guidelines revision support and clinician training on new ARV medications containing DTG
+2 years
of acceleration in development, manufacturing, regulatory approval, and commercialization of key pediatric ARV products
US$120
per person, per year expected reduction in cost of darunavir for HIV through optimized manufacturing processes

Join Our Team

CHAI is looking for dynamic and self-motivated individuals who are committed to strengthening health systems around the world and expanding access to care and treatment of HIV/AIDS, malaria, and other illnesses.

View All CHAI Positions View Program Positions

Join Our Team

CHAI is looking for dynamic and self-motivated individuals who are committed to strengthening health systems around the world and expanding access to care and treatment of HIV/AIDS, malaria, and other illnesses.

View All CHAI Positions View Program Positions
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