Overview

CHAI began work in South Africa in 2003, supporting the government to develop an operational plan to improve access to antiretroviral treatment for HIV. When the plan was rolled out in 2008, CHAI worked with the National Department of Health to prepare for its launch and to offer technical assistance to accelerate the scale-up of HIV treatment. We utilized our market shaping approach to help reduce the costs of these critical medications to save the government over $1 million per day.

Since that time, CHAI has supported the government to achieve a number of live-saving firsts. South Africa has anchored many global pricing deals that CHAI has helped negotiate to reduce the costs of essential health products. Since 2010, South Africa has saved more than US$2 billion on HIV and tuberculosis medicines, diagnostics, and vaccines – and paved the way for other countries to adopt the same products at reduced prices. Today, the country has the largest HIV program in the world. With CHAI’s support, the government has increased the number of patients on treatment from 700,000 in 2008 to more than 4.2 million in 2019. The impact has been profound and lasting. South Africa has gone from a life expectancy of 53 years to 62 years, with most of these gains attributed to the expansion of the HIV program. Recently, the government was a key buyer in a ground-breaking deal to reduce the cost of TLD, a best-in-class antiretroviral drug that treats HIV. This is expected to save the government close to a billion dollars over the next five years.

CHAI supports the government in other areas, including combatting drug-resistant tuberculosis by introducing better and more affordable drugs and diagnostic tests; helping eliminate malaria in three key provinces; increasing access to reproductive health tools to save the lives of women; improving the country’s health financing systems; and supporting the design and rollout of a national health insurance plan.

Our Work
Woman wearing a TB mask points at a whiteboard in South Africa.

March 24, 2020

How do we end the TB epidemic by 2035?

Finding and treating people with tuberculosis is critical to slow the disease. Preventing it in the first place will help end the epidemic.

Read More

December 21, 2018

CHAI joins the International Decision Support Initiative (iDSI)

CHAI is proud to join the International Decision Support Initiative (iDSI). iDSI is a global network of health, policy and economic experts supporting low- and middle-income countries to make healthcare investment decisions that reflect the best value-for-money. CHAI is one of several partners who will expand the group’s global network of expertise and cross-country experience....

Read More

December 1, 2018

World AIDS Day: The invaluable voice of community in accelerating access to optimal HIV treatment

Sitting and talking with other people living with HIV at a health facility in Uganda, Zane* no longer felt alone. Unlike many of the others there who remained on efavirenz (EFV), he had recently switched to a new treatment regimen that includes dolutegravir (DTG) and could not believe how much better he felt. On DTG,...

Read More

December 22, 2017

How a landmark drug deal will reduce side effects and help people living with HIV stay on treatment

This World AIDS Day, we celebrate the tremendous progress that has been made in response to the HIV/AIDS epidemic, with more than 20 million people living with HIV accessing life-saving antiretroviral treatment (ART) as of today. The incredible scale up of ART in developing countries, with affordable generic drugs widely available and the majority of...

Read More
Woman wearing a TB mask points at a whiteboard in South Africa.

March 24, 2020

How do we end the TB epidemic by 2035?

Finding and treating people with tuberculosis is critical to slow the disease. Preventing it in the first place will help end the epidemic.

Read More

December 21, 2018

CHAI joins the International Decision Support Initiative (iDSI)

CHAI is proud to join the International Decision Support Initiative (iDSI). iDSI is a global network of health, policy and economic experts supporting low- and middle-income countries to make healthcare investment decisions that reflect the best value-for-money. CHAI is one of several partners who will expand the group’s global network of expertise and cross-country experience....

Read More

December 1, 2018

World AIDS Day: The invaluable voice of community in accelerating access to optimal HIV treatment

Sitting and talking with other people living with HIV at a health facility in Uganda, Zane* no longer felt alone. Unlike many of the others there who remained on efavirenz (EFV), he had recently switched to a new treatment regimen that includes dolutegravir (DTG) and could not believe how much better he felt. On DTG,...

Read More

December 22, 2017

How a landmark drug deal will reduce side effects and help people living with HIV stay on treatment

This World AIDS Day, we celebrate the tremendous progress that has been made in response to the HIV/AIDS epidemic, with more than 20 million people living with HIV accessing life-saving antiretroviral treatment (ART) as of today. The incredible scale up of ART in developing countries, with affordable generic drugs widely available and the majority of...

Read More
Our Programs
Our Donors

Join Our Team

CHAI is looking for dynamic and self-motivated individuals who are committed to strengthening health systems around the world and expanding access to care and treatment of HIV/AIDS, malaria, and other illnesses.

View All CHAI Positions View Country Positions

Join Our Team

CHAI is looking for dynamic and self-motivated individuals who are committed to strengthening health systems around the world and expanding access to care and treatment of HIV/AIDS, malaria, and other illnesses.

View All CHAI Positions View Country Positions