Market growth drivers
Demand for prostheses is expected to double by 2050, particularly in LMICs:
- Increase in trauma incidence: Trauma is a major cause of limb amputation, accounting for around 50 per cent of amputations,
and up to 80 per cent of amputations are in LMICs. , , Globally, the prevalence of traumatic amputations increased by 49 per cent between 1990 and 2019. Risk factors for traumatic amputations in LMICs are especially common among older adults, as well as in unsafe working environments
leading to crush injuries or electrical burns, and traffic accidents.91
- Increase in non-communicable diseases: Patients with diabetes have a 30 times greater lifetime risk of undergoing an amputation:
80 per cent of all lower extremity non-traumatic amputations in the United States are caused by diabetes. , . In the United States, the number of amputations caused by diabetes is estimated to have increased by 24 per cent from 1988
to 2009. Furthermore, three out of four people in the diabetic population reside in LMICs. The number of diabetic cases worldwide
is expected to grow globally from an estimated 537 million (with approximately 400 million in LMICs) in 2021 to 783 million
in 2045.